Archives: Research

Basosquamous carcinoma involving the anterior skull base: a neglected tumor treated using intraoperative navigation as a guide to achieve safe resection margins

Gregoire C, Adler D, Madey S, Bell B, JOMS. 2011 Jan;69(1):230-6.

Abstract

Basosquamous carcinoma (BSC) or metatypical carcinoma is a rare and controversial form of basal cell carcinoma (BCC) that was first described by MacCormac in 1910. Numerous theories have been described in the literature regarding its origin but it is generally accepted as a variant of BCC that differentiates into squamous cell carcinoma (SCC). At present, it has an unsatisfactorily established phenotype but is considered to behave more like an SCC than a BCC. A reflection of this fact is its more aggressive nature with a significantly increased incidence of local and distant metastasis. It must be distinguished histologically from so-called “collision” tumors, which represent SCC and BCC arising as separate entities in the same area. We present a unique case of a neglected, large, and locally advanced case of BCC originating from the nose, but extending into the paranasal sinuses, orbit, and anterior skull base, that was treated with en bloc surgical resection using intraoperative navigation to assist in treatment planning and margin clearance.

Facial appearance following surgical treatment for obstructive sleep apnea syndrome

Goodday RG, Gregoire CE, General Dentistry, May 2008. Page 251-257.

Abstract:

Obstructive sleep apnea syndrome (OSAS) is a serious medical condition that is associated with numerous negative health side effects. The general dentist plays an invaluable role in identifying patients with this condition. Certain OSAS patients receive significant medical and social benefits from orthognathic surgery to advance the maxilla, mandible, and chin. Anterior positioning of the maxilla and mandible is not only highly successful for curing OSAS but also results in favorable facial esthetic changes.

The Need for Concomitant Bone Grafting During Maxillomandibular Advancement for the Treatment of Obstructive Sleep Apnea Syndrome

Goodday RG, Gregoire CE., JOMS. 2007 Sept; 65(9):42.

Abstract

Obstructive sleep apnea syndrome (OSAS) is a serious, potentially life-threatening medical condition with a wide range of deleterious health side effects. The benefits of Maxillomandibular Advancement (MMA) surgery to treat OSAS in selected patients are well recognized. Controversy exists regarding the need to perform a concomitant bone graft to ensure stability and good bone healing at the osteotomy site in MMA patients. This additional procedure increases surgical time, expense and morbidity. The purpose of this study is to determine the incidence of post-operative mobility of the maxilla and or mandible in a group of patients undergoing MMA without concomitant bone graft for the treatment of OSAS.

Management of Nasofrontal Fractures

Gregoire C, Morrison A., OMFS Clinics of North America. 2013

Repair of fractures involving the nasofrontal region remains a mainstay of contemporary oral and maxillofacial surgery. This article discusses the epidemiology of these injuries, anatomy of the area, and management of these fractures with insight into potential complications. These include fractures of the frontal sinus, naso-orbital-ethmoidal region, root of the nose, and associated adjacent structures.

Recurrent Osseous choristoma involving the mandibular buccal vestibule: a case report

Gregoire C, Davis C, Bullock M, Steeves T. Recurrent Osseous choristoma involving the mandibular buccal vestibule: a case report. Int J Oral and Dent Health. 2015 April.

Abstract

This case report is the third ever reported of a recurrent intraoral osseous choristoma. The lesion had manifested twice in the left mandibular buccal vestibule of a 63-year-old Caucasian female.

The patient was treated with wide local excision on both occasions. We believe that the lesions may have arisen as a result of previous trauma, although the exact etiology of the lesions is unknown. Interestingly, the recurrent lesion contained satellite nodules of bone, which suggests that the osseous choristoma may recur yet again.